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Posted October 31, 2024

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The Ohio State University Comprehensive Cancer Center (OSUCCC)

Pelotonia Institute for Immuno-Oncology (PIIO)

Senior Research Scientist

Columbus, Ohio 43210

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The Immune Monitoring and Discovery Platform (IMDP), within the OSUCCC-James Pelotonia Institute for Immuno-Oncology, delivers cutting-edge technology to analyze the immune system’s response to cancer immunotherapy. IMDP resources include Cytek Aurora Spectral Cell Sorter, Cytek Aurora Spectral Analyzer, Cytek Northern Lights, BD FACSMelody, PhenoImager HT (Vectra), EVOS, Xenium Analyzer and more. The IMDP is seeking an innovative Senior Research Scientist.

Job Duties include:

• Instrument maintenance, standardization, and quality assurance: Establish and/or modifies and/or implements Standard Operating Procedures for routine instrument maintenance and performance evaluation.

• Perform instrument setup and acquisition of samples independently.

• Perform calibration/alignment, maintenance, trouble-shooting, repair of cytometers and associated facility instruments.

• Document instrument performance, maintenance, service, and corrective actions.  

• Provide training for technicians and investigators with respect to the basics of the technology, instrument startup/shutdown and maintenance, data acquisition and transfer, and data analysis as needed.

• Educate core laboratory clients with respect to sample requirements for specific experimental goals.

• Experimental design and optimization with the laboratory Director to advise investigators regarding experimental design and data analysis.

• Work with investigators to explore and optimize current and emerging techniques.

• Work independently or together with Director to establish analysis strategies. Present novel assays and techniques to research group.   

• Assess inventory and order supplies when needed.

• Conduct operations of the facility within safety guidelines for instrument operation, as well as chemical and biological safety standards.

• Maintain reporting and billing, process costing and fee development, budget development and management.    

• Maintain technical currency, identify, and assess developing technologies, platforms, reagents, and methods.

• Import and deploy as appropriate.           

Minimum Qualifications:

• Master's Degree, PhD or equivalent experience required.

• 5-6 years of relevant experience required.

• 6-8 years of relevant experience preferred.

Experience:

• Proficient knowledge of immunology.

• Demonstrated success training and supervising others.

• Demonstrated experience with data analysis platforms and reducing that data to figures suitable for scientific presentations (e.g., FlowJo, DiVa, Omiq, InForm) and Microsoft Office products (e.g., Word, Excel, PowerPoint) and other common tools.

• Training in bacteriological, viral, chemical, and physical safety.

• Proficiency with Macintosh and PC computers and handheld devices.

• Able to work safely in a BSL2 environment.

• Requires successful completion of a background check; selected candidate may be requested to completed a pre-employment physical including a drug screen.

Additional Information:

Send cover letter, CV, contact information for three references via email to Dr. Yoshi Koguchi at yoshinobu.koguchi@osumc.edu

About Us:
The PIIO is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels (https://cancer.osu.edu/piio). Launched in July 2019 as part of a $102 Million pledge from Pelotonia (pelotonia.org), the PIIO represents Ohio State's commitment to grow the exciting area of immuno-oncology. Led by founding director and renowned immunologist Zihai Li, MD, PhD, the PIIO builds upon a rich portfolio of active investigator-initiated IO clinical trials being conducted at the OSUCCC – James.

Research in the PIIO centers on Systems IO (a systems-wide strategy to study the anti-cancer immune response holistically to discover the next IO breakthroughs and create effective cancer immunotherapies) and Translational IO (where we turn discoveries into new or improved cancer treatments and broaden the indications and patient populations that can be treated with cellular therapy). Our Immune Monitoring and Discovery Platform (IMDP) supports each center, providing comprehensive cell-based and molecule-based immunoassay services to support basic, translational, and clinical IO studies. The PIIO’s Immuno-Oncology Informatics Group (IOIG) provides data analytics for flow and mass cytometry, bulk and single-cell RNA-Seq, spatial transcriptomics and imaging, neoantigen discovery, and more.

The OSUCCC – James is a National Cancer Institute (NCI)-designated comprehensive cancer center, rated “Exceptional,” the highest rating given to cancer centers by the NCI; is one of only a few centers funded by the NCI to conduct phase I, II and III clinical trials on novel anticancer drugs; and includes the third-largest freestanding cancer hospital in the country.

The Ohio State University is an equal opportunity employer.

All qualified applicants will receive consideration for employment without regard to age, ancestry, color, disability, ethnicity, gender identity or expression, genetic information, HIV/AIDS status, military status, national origin, race, religion, sex, gender, sexual orientation, pregnancy, protected veteran status, or any other basis under the law.

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Posted October 16, 2024

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NYU Langone Health

Director of Cytometry and Cell Sorting (CCSL) NYU Grossman School of Medicine

New York, NY

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Join NYU Langone's Division of Advanced Research Technologies (DART) as the Director of the Cytometry and Cell Sorting Laboratory (CCSL). In this pivotal role, you will lead a state-of-the-art core facility dedicated to advancing basic, clinical, and translational research through cutting-edge cytometry technologies. Collaborating closely with principal investigators, you will provide scientific expertise and oversee all operational aspects, including budgeting, staff management, and project workflows. Your responsibilities will encompass developing educational programs, advancing technology research collaborations, and ensuring high-quality results to our scientific community. The ideal candidate will hold a PhD in a relevant biomedical field, possess at least 3 years of flow cytometry experience, and have a minimum of one year of supervisory experience. If you're passionate about facilitating innovative research and fostering collaboration across disciplines, we invite you to apply and help shape the future of translational research at NYU Langone.

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Apply here: https://apply.interfolio.com/156526

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Posted October 16, 2024

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Slingshot

Staff Scientist (Scientist 3) – Protein Conjugation & Flow Cytometry

Emeryville, California, United States

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Description

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Slingshot Biosciences is a growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications.  We currently have a suite of products that allow for rapid, stable instrument deployment and are poised to make headway into clinical markets with controls for engineered cell therapies.  At Slingshot, we value diversity and believe that a variety of backgrounds and experiences leads to more innovative ideas and a better understanding of our customers. Passion is at the core of our values, and employees are encouraged to pursue their passions in their work and contribute to the company's overall mission.  We desire motivated team members who appreciate the freedom to be creative and think outside the box to solve problems.  We offer an environment where employees are empowered to take ownership of their work and to contribute new ideas.  In everything we do, we are dedicated to delivering top-quality products to positively impact patient care.

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The Staff Scientist (Scientist 3), Protein Chemistry role will report to the Director of Biochemistry. They will join our team and help in the production of biochemically modified synthetic cells for the development of both custom and/or catalog products. They will also facilitate the transfer of our products from R&D to process development and manufacturing. To be successful, the Staff Scientist, Protein Chemistry will need experience in protein conjugation, working with various types of bioconjugation chemistries and understanding of both biochemistry and how to handle proteins. Familiarity with flow cytometry is preferred for product QC. This role will be a management and leadership position, and the candidates should have experience with managing direct reports, and be excited about bringing innovation and new ideas to the team. The Staff Scientist, Protein Chemistry should be comfortable writing technical reports and analyses of findings, with the goal of leading development projects and reporting and presenting results clearly to management and external stakeholders. This position will be on-site in Emeryville, CA. We are a small but growing team, and the applicant must be comfortable in a dynamic, fast-paced environment. Self-motivated and driven applicants of all experience levels are encouraged to apply.

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Responsibilities

• Contribute to R&D efforts in the biochemistry group, with a focus on development of products intended for flow cytometry applications. This work will be supporting the production of our custom products pipeline.

  • Protein conjugation related product development work

  • Antibody panel design for Flow Cytometry based assays

  • Flow cytometry assays on different conventional and spectral flow cytometry instrumentation

• Employ bioconjugation techniques to various biomarkers of interest for the development of synthetic cells and suggest new ideas to improve ongoing conjugation work.

• Do deep dives of literature to determine the best experimental plans based on precedent, and independently drive and troubleshoot projects with your direct report(s).

• Help develop and test new products addressing customer needs in the cell therapy and diagnostics space, and represent the biochemistry team at the project meetings.

• Designing experiments to pressure test protocols to ensure their robustness. Diligent and detailed record keeping of experimental protocols.

• Transfer protocols and SOPs to the process development and manufacturing groups as needed

• Work in the lab on independent projects while also managing a direct report who will support those projects

  • Lead projects and drive innovation

  • Train and mentor direct reports

  • Assign projects, plan their experiments and support troubleshooting while working on your own research projects and managing timelines

  • Report team’s progress to management

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Requirements

• Ph.D. in a relevant field with 6-8 years of industry experience, or equivalent

• Background in biochemistry, protein chemistry, chemical biology, molecular biology, or an equivalent field

• Experience with management and mentorship while also working on their own experimental projects

• Experience with conjugation chemistry

• Experience with flow cytometry

• Experience with protein purification and basic molecular biology is nice to have

• Able to multitask, prioritize and manage time effectively.

• Strong communication and presentation skills

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Nice to have

• Understanding of relevant steps of gene-to- protein process, including construct design, molecular cloning, protein expression, purification, and characterization (bacterial and/or mammalian systems)

• Experience in developing and optimizing purification protocols for different recombinant proteins (with and without affinity tags) using various chromatographic methods (affinity, IEX, SEC, etc) and purification systems (e.g., AKTA)

• Understanding or interest in the cell therapy and diagnostics space

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Our salary ranges are calculated by role and level. Your position within that range will be determined by your job-related knowledge, skills, experience, relevant education, and training/certifications. In addition to those factors, we also examine internal equity as well as consider current market rate, and title may be assessed one level lower or higher accordingly. After you join the company your performance, contributions, and results along with business and organizational needs will affect your base salary. The base salary range for this full-time position is between $145,000 - $185,000 + equity + benefits.

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Apply here!

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Posted October 16, 2024

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BD Biosciences

Research Reagent Specialist I

USA NJ - Franklin Lakes

USA - New York - New York

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BD is one of the largest global medical technology companies in the world. Advancing the world of health™ is our Purpose, and it’s no small feat. It takes the imagination and passion of all of us—from design and engineering to the manufacturing and marketing of our billions of MedTech products per year—to look at the impossible and find transformative solutions that turn dreams into possibilities.  

We believe that the human element, across our global teams, is what allows us to continually evolve. Join us and discover an environment in which you’ll be supported to learn, grow and become your best self. Become a maker of possible with us. 

This role offers you the opportunity to use your scientific expertise and consultative sales skills to grow BD Bioscience research reagents within the Biotech, Academic, CRO and Pharma industry.  Primary responsibilities include developing and crafting new business opportunities through promoting the reagent portfolio, working strategically with their local area team and specialist.   The RRS will focus on new acquisition of customers and early account development.  They will convert competitive business in the assigned territory, with the intent of growing revenue while balancing reasonable margins. The RRS is directly responsible for achieving their territory sales growth.

 

 

Responsibilities:

• You will be responsible for growing the research reagent business and managing a sales budget within an assigned territory. 

• Achieve revenue goals by growing customer base and product usage in the territory

• Utilize business systems and tools to effectively forecast monthly sales for key accounts and overall territory.

• Develop and maintain distribution relationships by actively communicating, strategizing and shared working days in the field.   

• Manage territory activities through Salesforce.com, including, but not limited to, entering contacts, and pricing/quotation requests.

• Develop and maintain adequate short/long term sales pipeline to consistently generate profitable revenue.

• Build team relationships with other BD Biosciences Associates, including Sales, Service, and Applications Support to improve sales revenues and promote customer-focused system solutions.

• Perform other related duties and assignments as the need arises.

 

Qualifications:

Required:

• A minimum of a Bachelor's degree, in a scientific field.

• Laboratory experience, highly preferred in flow cytometry.

• A valid driver's license.

• Ability to travel a minimum of 50% of the time.

• Effective interpersonal, written, and oral communications skills.

• Effective organization and planning skills.

• Effective selling and negotiation skills.

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Strongly Preferred: 

• BS Degree in Biology or other Medical/Life Sciences-related field

• Familiarity with Life Science Research and Pharma/Biotech/Academic accounts.

• Sales or customer service experience

• Flow Cytometry knowledge and working experience highly preferred.

• Ability to adapt to changing business environment and continually meet customer needs.

• Effective meeting, training, and presentation skills.

• Effective decision making/problem-solving skills.

• Effective digital literacy, i.e., Outlook, Excel, Word, PowerPoint, SalesForce.com, etc.

 

To Apply, please follow the link below:

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https://bdx.wd1.myworkdayjobs.com/EXTERNAL_CAREER_SITE_USA/job/USA-NJ---Franklin-Lakes/Research-Reagent-Specialist-I_R-500287

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Posted August 28, 2024

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University of Virginia Flow Cytometry Core Facility

Flow Cytometry Core Specialist

Charlottesville, VA

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The University of Virginia Flow Cytometry Core Facility, an ISAC recognized Shared Resource Lab, is seeking an experienced Flow Cytometry Core Specialist. The Flow Cytometry Core Facility is equipped with an array of advanced analytical cytometers, cell sorters, and a mass cytometer.  The Flow Core provides services to a broad array of investigators, both inside and outside UVA. The ideal candidate will have expertise in flow cytometry, including instrument maintenance, troubleshooting, data analysis, and client support. 

 

Join this exciting opportunity to work with advanced flow cytometry technologies and collaborate with researchers.

 

Application and details can be found:

https://uva.wd1.myworkdayjobs.com/UVAJobs/job/Charlottesville-VA/Flow-Cytometry-Core-Specialist_R0064400

 

https://uva.wd1.myworkdayjobs.com/UVAJobs/job/Charlottesville-VA/Lab-Specialist_R0064401

 

Please reach out with any questions.

 

Best

 

Michael Solga, MS, SCYM (ASCP)
Director, Flow Cytometry Core
University of Virginia 
School of Medicine
mds4z@virginia.edu

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Posted May 21, 2024

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CellNetix Pathology & Laboratories

Flow Cytometry Technologist (ASCP)

Tukwila, WA

 

ABOUT US

 

CellNetix Pathology & Laboratories is headquartered in the Seattle area in our state-of-the-art Central Processing Laboratory. As one of the largest AP labs in the United States, with over 300 staff members and 60+ distinguished Pathologists, we offer some of the most technologically advanced resources and service menus in the region. In addition, our cutting-edge Molecular Laboratory with next-generation sequencing offers groundbreaking personalized medicine testing. Our lab continues to grow in technology and scientific advancement while offering our employees a wide array of training and career progression pathways in Administration, Laboratory and Hospital Support, Histology, Cytology, Infectious Diseases, Molecular, Grossing and more. If our mission of patient care resonates with you, Come Grow with Us in Pursuit of Excellence.

 

Position Summary:

 

We are seeking a strong FLOW Cytometry tech to join our outstanding team in our state-of-the-art laboratory. The Flow Cytometry Technologist duties will include assay development, validation, overall test monitoring and troubleshooting. The position is responsible for accurate reporting of results, quality control, training new employees, equipment maintenance and all other duties assigned by the supervisor.

 

Position Schedule: This is a Full-Time, hourly position. Training period will be at a Day Shift, then will switch to 3rd shift.

 

Qualifications and Experience:

• Medical Laboratory Scientist (MLS, ASCP-Certified)

  • New graduates encouraged to apply

  • Flow cytometry experience preferred

• or Medical Laboratory Technician (MLT, ASCP-Certified)

  • New graduates encouraged to apply

  • Flow cytometry experience preferred

• or 4-year degree in biological sciences/chemistry (or US-equivalent)

  • High-volume sample preparation and testing in a flow laboratory required

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Compensation

$34.60 - $54.41 Hourly

Benefits

 

CellNetix offers comprehensive benefits plan in addition to competitive pay. Some of the most popular benefits include:

• Free parking onsite

• Generous company paid healthcare (medical, vision, dental, prescription) plan options.

• Substantial 401K company match.

• Starting paid time off accrual of up to 15 days/year plus 8 paid holidays.

• Life and disability insurance.

• Fully subsidized ORCA card and free parking at most sites.

• Our most recent benefit addition of Norton LifeLock Identity Protection at no employee cost.

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IMPORTANT NOTICE: As a healthcare organization we are committed to providing a healthy and safe environment. We require a criminal history background check and drug test for all final candidates. Additionally, CellNetix has a mandatory COVID-19 vaccination policy.

See full job description here and APPLY!

Please contact recruiting@cellnetix.com for more information.

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